Leaky Gut Test (Lactulose & Mannitol)
A functional test of intestinal permeability at home. Lactulose and mannitol urine test with the L/M ratio, analysed in a NATA-accredited AU lab.
Product details: AUD 269 — InStock — SKU 2011 — GetTested
About this test – Leaky Gut Test (Lactulose & Mannitol)
When is this test relevant?
Digestive symptoms such as bloating, discomfort, or irregular bowel habits
Suspected food sensitivities
Ongoing gut-related concerns without a clear explanation
Interest in a functional assessment of intestinal permeability
As part of a broader evaluation of gut health
How it works
Drink a solution containing lactulose and mannitol as instructed
Collect a urine sample at home over the specified collection period
Send your sample to the laboratory using the prepaid return envelope
Your sample is analysed at a NATA-accredited laboratory in Australia, following ISO 15189 standards
Receive your digital results within 5 days
You can also use our AI-based chat to help interpret your results.
Key information
Sample type: Urine
Markers: Lactulose, mannitol, and the lactulose/mannitol ratio
Method: Functional assessment based on absorption and urinary excretion
Turnaround time: Within 5 days from when the lab receives your sample
Results: Delivered digitally
Laboratory: NATA-accredited laboratory (ISO 15189)
Shipping: Return shipping included
Accredited Laboratory
Your sample is analysed at a NATA-accredited laboratory in Australia, operating in accordance with ISO 15189 standards for medical testing. This ensures that all analyses are performed using validated methods and strict quality control procedures.
Biomarkers included – Leaky Gut Test (Lactulose & Mannitol)
- Mannitol Recovery: Mannitol Recovery measures how much mannitol is recovered in urine after the test drink. Mannitol is a small sugar molecule that is normally absorbed through the small intestine. Because of this, mannitol recovery helps show whether the intestinal lining is absorbing small molecules as expected. Low mannitol recovery may suggest reduced absorption through the gut lining. In practical terms, this c
- Lactulose/Mannitol Ratio: Lactulose/Mannitol Ratio compares the recovery of lactulose and mannitol in urine after the test drink. Lactulose is a larger sugar molecule that mainly reflects gut barrier permeability, while mannitol is a smaller sugar molecule that reflects small intestinal absorption. The ratio helps show whether the gut lining is allowing larger molecules through more easily than expected in relation to its
- Lactulose Recovery: Lactulose Recovery measures how much lactulose is recovered in urine after drinking the test solution. Lactulose is a larger sugar molecule that normally passes through the intestinal lining only in small amounts. Higher lactulose recovery may suggest that the gut barrier is more permeable than expected. In practical terms, this can mean that the gut lining is under strain and less effective at ke
How to prepare – Leaky Gut Test (Lactulose & Mannitol)
Fast for 8 hours prior to test. Avoid sugar, fruit, and alcohol for 24 hours. Brief pause of NSAIDs (48-72 hours) recommended under physician guidance.
Frequently asked questions – Leaky Gut Test (Lactulose & Mannitol)
How long do I need to fast before the test?
You should fast for at least 8 hours, typically overnight, before starting your urine test for leaky gut. Additionally, please avoid all sugars, fruits, and alcohol for 24 hours prior to sample collection to ensure accuracy.
Is this the same as a SIBO test?
No, these are different diagnostic tools. A SIBO test analyzes hydrogen and methane gases in the breath to detect bacterial overgrowth. This intestinal permeability lab test measures the physical movement of sugar molecules through the gut lining via a urine sample.
Can I take medications or supplements before testing?
NSAIDs like Ibuprofen or Aspirin and high-dose corticosteroids should be avoided for 48-72 hours before testing, as they can artificially increase permeability. Always consult your healthcare provider before pausing any prescribed medications.
Customer reviews – Leaky Gut Test (Lactulose & Mannitol)
4.6/5 (5)
- 4/5 — Exactly what my nutritionist needed. Glad I did it.
- 5/5 — Super fast delivery and easy to follow instructions.
- 5/5 — Actually got my results in 4 days. Very impressed with the speed.
- 4/5 — Straightforward home test for gut health.
- 5/5 — Finally some objective data for my bloating issues! The digital report was clear and informative.