Neurotransmitter Test (Medium)

About this test – Neurotransmitter Test (Medium)

Why test your neurotransmitter levels?

Neurotransmitters regulate mood, stress response, sleep, and cognitive function, and imbalances may develop over time due to stress, lifestyle, or other factors.

This test may be relevant when exploring:

• Low mood or lack of motivation

• Stress or difficulty coping with stress

• Sleep disturbances

• Difficulty with focus or concentration

• Feelings of restlessness or low resilience

• Sensitivity to stress or overstimulation

How it works

1. Collect a urine sample at home

2. Send your sample to the laboratory using the prepaid return envelope

3. Your sample is analysed using validated laboratory methods to ensure accurate and reliable results

4. Receive your digital results within 14 days

You can also use our AI-based chat to help interpret your results.

Key information

• Sample type: Urine

• Turnaround time: 14 days from when the lab receives your sample

• Results: Delivered digitally

• Laboratory: Accredited laboratory

• Shipping: Return shipping included

Accredited Laboratory

Your sample is analysed at a NATA-accredited laboratory in Australia, operating in accordance with ISO 15189 standards for medical testing. This ensures that all analyses are performed using validated methods and strict quality control procedures to provide accurate and reliable results.

Biomarkers included – Neurotransmitter Test (Medium)

• GABA: Calming Neurotransmitters — GABA (gamma-aminobutyric acid) is the brain’s primary inhibitory neurotransmitter and helps regulate neuronal excitability by promoting calm signaling and preventing overstimulation. It counterbalances excitatory neurotransmitters such as glutamate and is involved in pathways related to stress regulation, sleep, mood, and muscle tone. Altered GABA signaling has been linked to conditions such as an
• Glycine: Calming Neurotransmitters — Glycine is the simplest amino acid and is involved in protein synthesis and many important metabolic pathways. It contributes to neurotransmission in the nervous system and is a building block for compounds such as glutathione (antioxidant defense), creatine (energy metabolism), and heme (oxygen transport). Glycine can be produced in the body, but requirements may increase under certain conditions
• Serotonin: Calming Neurotransmitters — Serotonin is a key neurotransmitter often called the “happiness chemical,” involved in regulating mood and emotional well-being. It also plays important roles in sleep, digestion, bone health, and blood clotting. Mainly produced in the gut, serotonin influences both the brain and body by affecting various physiological functions and emotional states. Imbalances in serotonin levels can have signifi
• Histamine: Stimulating Neurotransmitters — Histamine is a biogenic amine and signaling molecule involved in immune responses, gastric acid secretion, and neurotransmission. It is released by mast cells and basophils during allergic reactions and inflammatory responses, causing vasodilation, increased vascular permeability, and smooth muscle contraction. Histamine also regulates stomach acid production and functions as a neurotransmitter in
• Phenylethylamine (PEA): Stimulating Neurotransmitters — Phenylethylamine (PEA) is a trace amine involved in the brain’s signalling systems. It is linked to mood, attention, motivation and the activity of other neurotransmitters such as dopamine and noradrenaline. PEA is sometimes described as a stimulant like signalling molecule because it can support alertness, focus and reward related pathways. Changes in PEA levels may reflect shifts in neurotransmi
• Glutamate: Stimulating Neurotransmitters — Glutamate is a key excitatory neurotransmitter in the brain that plays a vital role in cognitive processes such as learning and memory. It is essential for brain development and synaptic plasticity. However, excessive glutamate levels can cause neuronal overstimulation, leading to potential neurotoxicity. This balance makes glutamate critical for normal brain function while also linking it to vari
• Dopamine: Dopamine and Adrenaline Pathway Markers — Dopamine is a key neurotransmitter that supports the brain’s reward and motivation systems. It plays essential roles in mood regulation, pleasure, focus, memory, and movement control. Imbalances in dopamine levels can affect mental well-being and are linked to conditions such as depression, anxiety, and Parkinson’s disease.
• Adrenaline: Dopamine and Adrenaline Pathway Markers — Adrenaline is a hormone and neurotransmitter released during stressful or threatening situations. It activates the body’s fight-or-flight response, increasing heart rate, blood pressure, and mental alertness. Elevated levels may reflect acute stress, while imbalances can affect how the body responds to pressure and external stimuli.
• Noradrenaline: Dopamine and Adrenaline Pathway Markers — Noradrenaline plays a central role in the body’s stress response and helps regulate alertness, focus, and blood pressure. It works closely with adrenaline and dopamine to support mental clarity and energy levels. Imbalances may affect concentration, stress tolerance, and overall nervous system activity.
• Noradrenaline/Adrenaline ratio: Neurotransmitter Balance Ratio — The noradrenaline/adrenaline (NA/A) ratio is a measure that reflects the balance between two key stress hormones — noradrenaline (norepinephrine) and adrenaline (epinephrine). Both play vital roles in the body’s fight-or-flight response, influencing heart rate, blood pressure, and energy mobilization. This ratio can shift in response to factors such as stress, physical activity, and overall health
• Creatinine: Urine Concentration Marker — Creatinine is a waste product formed in muscles from the normal breakdown of creatine. It is released into the bloodstream and filtered by the kidneys, then excreted in urine. Because creatinine levels are influenced by how efficiently the kidneys filter blood, it is commonly used to assess kidney function. Elevated creatinine may indicate reduced kidney filtration or kidney disease, while low lev

How to prepare – Neurotransmitter Test (Medium)

Avoid amino acid supplements for 48 hours. Collect the second morning urine void. Do not stop prescription medications without consulting your doctor.

Frequently asked questions – Neurotransmitter Test (Medium)

How can a urine test measure brain chemistry?

Urinary neurotransmitters reflect the 'systemic' levels and 'turnover' of these chemicals. Research suggests these levels correlate with symptoms and can guide functional support, acting as a proxy for central nervous system activity.

Why is the Noradrenaline/Adrenaline ratio important?

The test measures both Noradrenaline and Adrenaline. The ratio between them helps determine if the body is over-converting or failing to convert these stress hormones, which is a clinical indicator of adrenal fatigue or chronic stress.

Is the sample collection time-sensitive?

Standard collection requires a second morning void (the second time you urinate after waking up) for the most accurate representative sample of your baseline levels.

Do I need to stop supplements or medications before the test?

Most clients are advised to avoid amino acid supplements (like 5-HTP, L-Theanine, or Tyrosine) for 48 hours prior to collection. Consult your physician regarding prescription medications such as SSRIs before testing.

Customer reviews – Neurotransmitter Test (Medium)

4.6/5 (5)

• 4/5 — Very interesting data. Waiting 2 weeks for results was a bit long, but the report was very detailed.
• 5/5 — This helped me understand my stress response much better.
• 5/5 — Easy to follow instructions and the kit arrived quickly.
• 5/5 — Very convenient way to check my serotonin at home.
• 4/5 — Straightforward collection. Wish it was a bit cheaper but the info is solid.